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Does a cloned animal have the same DNA as the genetic donor?

September 8, 2020

Yes, an animal produced through cloning technology carries a nuclear genome (DNA) that is an exact genetic match to the donor. The nuclear genotype, used for breed registry DNA genotyping, will be identical to the genetic donor that provided the tissue sample for Genetic Preservation or cell line creation. If the breed utilizes genomic evaluations, the cloned animal’s genomics will also match the donor.

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How does the cloning process work?

September 8, 2020

The word “cloning” is simply a term to describe Somatic Cell Nuclear Transfer (SCNT). Once cells are produced from the tissue sample provided by a genetic donor, they are combined with an enucleated oocyte (unfertile egg with the nucleus removed) and fused together using a process called electrofusion. The resulting embryos are cultured and transferred into recipient mothers within one week, with variation per species. “Dolly the Sheep” was the first mammal to be produced using SCNT cloning technology more than 20 years ago.

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What is a cloned animal?

September 8, 2020

A cloned animal is a genetic twin to an existing animal, just born at a later place in time.

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How can I preserve the genetics of my elite animal indefinitely?

September 8, 2020

To preserve an elite animal’s genetics, a tissue sample is collected from the ear or tail and cultured into a cell linethrough Genetic Preservation (GP). These cells are cryopreserved for future use in the cloning process. For a more economical option, the Express Tissue Bank (ETB) allows producers to store a large number of samples or keep genetic material on hand without an immediate cloning commitment. In this program, the tissue sample is frozen intact and can later be cultured into a GP cell line if cloning is desired.

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Why do livestock breeders use cloning technology?

September 8, 2020

Cloning allows progressive producers to replicate their most valuable animals, advancing their goals for healthier, more efficient livestock and higher-quality food products. By preserving superior genetics, cloning helps create a more consistent supply of desirable traits, such as tender, flavorful beef. Cloning also provides a solution for animals lost early in their breeding careers due to injury or death—ensuring their genetic potential isn’t lost. Additionally, it extends the influence of elite animals by increasing embryo or semen production. For clients with exceptional castrated males (steers, geldings, barrows, wethers), cloning offers the unique opportunity to produce an intact male for breeding.

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